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Ohio State football game Saturday: Ohio State vs. Notre Dame odds and prediction for Week 1

By Ryan Stano

Aug 11, 2022; Columbus, OH, USA; Ohio State Buckeyes quarterback C.J. Stroud (7) throws in front of quarterback Kyle McCord (6) during football camp at the Woody Hayes Athletic Center. Mandatory Credit: Adam Cairns-The Columbus DispatchOhio State Football Camp
Aug 11, 2022; Columbus, OH, USA; Ohio State Buckeyes quarterback C.J. Stroud (7) throws in front of quarterback Kyle McCord (6) during football camp at the Woody Hayes Athletic Center. Mandatory Credit: Adam Cairns-The Columbus DispatchOhio State Football Camp /
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It’s finally here! Game week. The Ohio State football team takes on Notre Dame in the regular season for the first time since the 90s. It’s a matchup between two top-five teams and will give an early shake-up to the college football landscape. Quite simply, it’s a huge game.

This is the first game that Jim Knowles will be coaching for the Buckeyes on the defensive side of the ball. How he coaches very well could be the difference in this game. Ohio State’s defense is the single biggest question mark in this game. If they play well, the Buckeyes should win. If they don’t Notre Dame will.

Both of these teams have their eyes set on making the College Football Playoff and competing for a national championship. Winning this game would go a long way for both programs to do just that. It will be a game that the entire country is focused on.

Ohio State football vs. Notre Dame odds Week 1

Right now, the Buckeyes are favored by 17 points according to WynnBET. That’s a pretty high spread when you consider the fact that both teams are ranked inside the top five of the polls. Perhaps bettors like how good the Ohio State offense is and the fact that the game is in the Shoe.

The moneyline sits at -745 for Ohio State. The over/under sits at 58.5 with -110 odds for each. Honestly, that seems low to me. I think the combination of Ohio State’s high-powered offense and their untested defense will provide us with a high-scoring affair.

Ohio State football vs. Notre Dame prediction Week 1

I have a lot of confidence in this Ohio State football team. The offense is going to be deadly all year. C.J. Stroud is going to be the best or second-best player on the field, depending on how good you think Jaxon-Smith-Njigba is. Both players should have a monster day.

Next. Predicting Ohio State's schedule, amount of wins. dark

In the end, I don’t think the Fighting Irish have enough firepower to keep it close. I see both teams being able to put up some points though. Give me the Buckeyes 45-20. I don’t see them slowing down for any reason in this game.

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